References

vtio

Вестник трансплантологии и искусственных органов

Russian Journal of Transplantology and Artificial Organs

1995-1191

Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation

10.15825/1995-1191-2010-4-53-60

vtio-345

Research Article

Обзор литературы

Literature Reviews

ТРАНСПЛАНТАЦИЯ ГЕПАТОЦИТОВ КАК МЕТОД ЛЕЧЕНИЯ ПЕЧЕНОЧНОЙ НЕДОСТАТОЧНОСТИ: ЭКСПЕРИМЕНТАЛЬНЫЙ И КЛИНИЧЕСКИЙ ОПЫТ

TRANSPLANTATION OF HEPATOCYTES AS THE METHOD OF TREATMENT OF LIVER FAILURE: EXPERIMENTAL AND CLINICAL EXPERIENCE

Шагидулин

М. Ю.

Shagidulin

M. Y.

dr.shagidulin@mail.ru

Онищенко

Н. А.

Onishchenko

N. A.

Крашенинников

М. Е.

Krasheninnikov

M. E.

ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, МоскваРоссияAcademician V.I. Shumakow Federal Research Center of Transplantology and Artificial Organs, MoscowRussian Federation

2010

09062014

124

ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XII No 4–2010

5360

2010

Шагидулин М.Ю., Онищенко Н.А., Крашенинников М.Е.

Shagidulin M.Y., Onishchenko N.A., Krasheninnikov M.E.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.transpl.ru/vtio/article/view/345

Перед выполнением трансплантации печени для коррекции и лечения тяжелой печеночной недостаточ- ности предложено несколько способов применения гепатоцитов: в экстракорпоральных устройствах, а также путем трансплантации гепатоцитов и имплантируемых модулей, созданных на основе тканевой инженерии. Способность здоровых и устойчивых к болезням гепатоцитов осуществлять свою функцию может позволить пациентам с декомпенсированными хроническими заболеваниями печени стабилизи- ровать свое состояние и дождаться донорского органа. В предлагаемом обзоре суммированы результа- ты экспериментальной и клинической терапии болезней печени методом трансплантации гепатоцитов.

For correction and treatment of liver failure before liver transplantation were proposed severe methods such as: extracorporal devices, transplantation of hepatocytes and implanted tissue-engineering units. The function of healthy hepatocytes presumes to stabilize the state of patients with chronic liver diseases and to wait a donor organ transplantation. In this review the results of experimental and clinical therapy of liver diseases by method of hepatocyte transplantation were summarized.

hepatocyte transplantationliver diseases

hepatocyte transplantationliver diseases.

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The authors declare that there are no conflicts of interest present.