<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2010-3-101-105</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-333</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Имплантаты и искусственные органы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Implants and Artificial Organs</subject></subj-group></article-categories><title-group><article-title>ПОКАЗАТЕЛЬ ОТНОСИТЕЛЬНОГО ОБЪЕМА КРОВИ КАК СРЕДСТВО ПРОФИЛАКТИКИ АРТЕРИАЛЬНОЙ ГИПОТЕНЗИИ В ХОДЕ ГЕМОДИАЛИЗА</article-title><trans-title-group xml:lang="en"><trans-title>RELATIVE BLOOD VOLUME: THE MEANS OF INTRADIALYSIS HYPOTENSION PREVENTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терехов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Terehov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">medick@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Строков</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Strokov</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва<country>Россия</country></aff><aff xml:lang="en">Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>05</day><month>06</month><year>2014</year></pub-date><volume>12</volume><issue>3</issue><issue-title>ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XII No 3–2010</issue-title><fpage>101</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Терехов В.А., Строков А.Г., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Терехов В.А., Строков А.Г.</copyright-holder><copyright-holder xml:lang="en">Terehov V.A., Strokov A.G.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/333">https://journal.transpl.ru/vtio/article/view/333</self-uri><abstract><p>Целью данной работы было определение закономерностей изменения относительного объема крови (ООК) в ходе гемодиализа и действенности различных мероприятий, направленных на поддержание вну- трисосудистого объема. Отслеживание ООК в ходе гемодиализа явилось действенной мерой как для профилактики интрадиа- лизной гипотензии, так и при отработке «сухого веса». Характер кривой ООК у стабильных пациентов на программном гемодиализе остается неизменным в течение многих лет. Высокое (более 6% на 1 литр) отношение максимального снижения ООК к объему ультрафильтрации (ООК/УФ) позволило выявить группу пациентов, у которых обеднение внутрисосудистого объема является основным механизмом раз- вития артериальной гипотензии в ходе сеансов лечения. Изолированная ультрафильтрация и гемодиа- фильтрация on line не позволили улучшить восполнение внутрисосудистого объема. Введение раство- ра альбумина позволяло снизить темп снижения ООК, а болюсное введение гипертонического раствора глюкозы повышало ООК на срок около получаса. У пациентов с острым повреждением почек показатель ООК не всегда оказывался достоверным. </p></abstract><trans-abstract xml:lang="en"><p>Intravascular volume preservation is the first choice measure for the prevention of intradialysis hypotension. At present there are devices that allow continuous monitoring of relative blood volume (RBV) changes during haemodialysis (HD). The aim of this research was to investigate (i) the regularity of RBV curve during haemo- dialysis and (ii) the efficacy of some measures for intravascular volume preservation. In patients with hyperhydration RBV curves were monotone; in all cases relation RBV/ ultrafiltration volume (UF) did not exceed 2,5%/L. In stable patients the RBV curve was immutable in the course of years. Patients with high RBV/UF ratio (&gt;6%/L) formed a high risk group. In these patients stability of RBV was more im- portant and more useful. Isolated UF did not decrease RBV drop, as well as haemodiafiltration online. Albumin administration allows to decrease RBV/UF ratio. After bolus of hypertonic dextrose solution RBV increased for about half of hour. In patients with acute renal injury RBV monitoring was far from reliability in many cases. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>относительный объем крови</kwd><kwd>гемодиализ</kwd><kwd>артериальная гипотензия.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>relative blood volume</kwd><kwd>hypotension</kwd><kwd>haemodialysis.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Строков А.Г., Терехов В.А. Показатель относитель- ного объема крови у пациентов на программном ге- модиализе // Нефрология и диализ. 2010. Т. 12. No 2. С. 101–105.</mixed-citation><mixed-citation xml:lang="en">Строков А.Г., Терехов В.А. Показатель относитель- ного объема крови у пациентов на программном ге- модиализе // Нефрология и диализ. 2010. Т. 12. No 2. С. 101–105.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Schroeder K.L., Sallustio J.E., Ross E.A. Continuous haematocrit monitoring during intradialytic hypoten- sion: precipitous decline in plasma refill rates // Nephrol. Dial. Transplant. 2004. Vol. 19. P. 652–656.</mixed-citation><mixed-citation xml:lang="en">Schroeder K.L., Sallustio J.E., Ross E.A. Continuous haematocrit monitoring during intradialytic hypoten- sion: precipitous decline in plasma refill rates // Nephrol. Dial. Transplant. 2004. Vol. 19. P. 652–656.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Lopot F., Nyiomnaitham V., Surov V. et al. Continuous blood volume monitoring and «dry weight» assess- ment // J. Ren. Care. Vol. 33. P. 52–58.</mixed-citation><mixed-citation xml:lang="en">Lopot F., Nyiomnaitham V., Surov V. et al. Continuous blood volume monitoring and «dry weight» assess- ment // J. Ren. Care. Vol. 33. P. 52–58.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Charra B., Chazot C. Volume control, blood pressure and cardiovascular function. Lessons from hemodialysis treatment // Nephron. Physiol. 2003. Vol. 93. P. 94–101.</mixed-citation><mixed-citation xml:lang="en">Charra B., Chazot C. Volume control, blood pressure and cardiovascular function. Lessons from hemodialysis treatment // Nephron. Physiol. 2003. Vol. 93. P. 94–101.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Barth C., Boer W., Garzoni D. et al. Characteristics of hypotension-prone haemodialysis patients: is there a critical relative blood volume? // Nephrol. Dial. Trans- plant. 2003. Vol. 18. P. 1353–1360.</mixed-citation><mixed-citation xml:lang="en">Barth C., Boer W., Garzoni D. et al. Characteristics of hypotension-prone haemodialysis patients: is there a critical relative blood volume? // Nephrol. Dial. Trans- plant. 2003. Vol. 18. P. 1353–1360.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">McIntyre C.W., Lambie S.H., Fluck R.J. Biofeedback controlled hemodialysis (BF-HD) reduces symptoms and increases both hemodynamic tolerability and dialy- sis adequacy in non-hypotension prone stable patients // Clin. Nephrol. 2003. Vol. 60. P. 105–112.</mixed-citation><mixed-citation xml:lang="en">McIntyre C.W., Lambie S.H., Fluck R.J. Biofeedback controlled hemodialysis (BF-HD) reduces symptoms and increases both hemodynamic tolerability and dialy- sis adequacy in non-hypotension prone stable patients // Clin. Nephrol. 2003. Vol. 60. P. 105–112.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Garzoni D., Keusch G., Kleinoeder T. et al. Reduced complications during hemodialysis by automatic blood volume controlled ultrafiltration // Int. J. Artif. Organs. 2007. Vol. 30. P. 16–24.</mixed-citation><mixed-citation xml:lang="en">Garzoni D., Keusch G., Kleinoeder T. et al. Reduced complications during hemodialysis by automatic blood volume controlled ultrafiltration // Int. J. Artif. Organs. 2007. Vol. 30. P. 16–24.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou Y.L., Liu H.L., Duan X.F. et al. Impact of sodium and ultrafiltration profiling on haemodialysis-related hy- potension // Nephrol. Dial. Transplant. 2006. Vol. 21. P. 3231–3237.</mixed-citation><mixed-citation xml:lang="en">Zhou Y.L., Liu H.L., Duan X.F. et al. Impact of sodium and ultrafiltration profiling on haemodialysis-related hy- potension // Nephrol. Dial. Transplant. 2006. Vol. 21. P. 3231–3237.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Donauer J., Kolblin D., Bek M. et al. Ultrafiltration pro- filing and measurement of relative blood volume as stra- tegies to reduce hemodialysis-related side effects // Ame- rican. J. of Kidney. Diseases. 2000. Vol. 36. P. 115–123.</mixed-citation><mixed-citation xml:lang="en">Donauer J., Kolblin D., Bek M. et al. Ultrafiltration pro- filing and measurement of relative blood volume as stra- tegies to reduce hemodialysis-related side effects // Ame- rican. J. of Kidney. Diseases. 2000. Vol. 36. P. 115–123.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Dasselaar J.J., Huisman R.M., de Jong P.E., Frans- sen C.F. Relative blood volume measurements during hemodialysis: comparisons between three noninvasive devices // Hemodial. Int. 2007. Vol. 11. P. 448–455.</mixed-citation><mixed-citation xml:lang="en">Dasselaar J.J., Huisman R.M., de Jong P.E., Frans- sen C.F. Relative blood volume measurements during hemodialysis: comparisons between three noninvasive devices // Hemodial. Int. 2007. Vol. 11. P. 448–455.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Mitra S., Chamney P., Greenwood R., Farrington K. The relationship between systemic and whole-body hemato- crit is not constant during ultrafiltration on hemodialy- sis // J. Am. Soc. Nephrol. 2004. Vol. 15. P. 463–469.</mixed-citation><mixed-citation xml:lang="en">Mitra S., Chamney P., Greenwood R., Farrington K. The relationship between systemic and whole-body hemato- crit is not constant during ultrafiltration on hemodialy- sis // J. Am. Soc. Nephrol. 2004. Vol. 15. P. 463–469.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Dasselaar J.J., Lub-de Hooge M.N., Pruim J. et al. Rela- tive blood volume changes underestimate total blood volume changes during hemodialysis // Clin. J. Am. Soc. Nephrol. 2007. Vol. 2. P. 669–674.</mixed-citation><mixed-citation xml:lang="en">Dasselaar J.J., Lub-de Hooge M.N., Pruim J. et al. Rela- tive blood volume changes underestimate total blood volume changes during hemodialysis // Clin. J. Am. Soc. Nephrol. 2007. Vol. 2. P. 669–674.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
