vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2009-4-103-109vtio-277Research ArticleОбзор литературыLiterature ReviewsПРИМЕНЕНИЕ ЭВЕРОЛИМУСА ПРИ ТРАНСПЛАНТАЦИИ ПОЧЕК ОТ ДОНОРОВ С РАСШИРЕННЫМИ КРИТЕРИЯМИTHE USE OF EVEROLIMUS IN KIDNEY TRANSPLANTATION FROM EXPANDED CRITERIA DONORSУльянкинаИ. В.UlyankinaI. V.РезникО. Н.ReznikO. N.onreznik@yahoo.comМойсюкЯ. Г.MoysyukY. G.ГУ «Санкт-Петербургский научно-исследовательский институт им. И.И. Джанелидзе», Санкт-ПетербургРоссияI.I. Djanelidze State Research Institute for Emergency, Saint-PetersburgRussian FederationФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова», МоскваРоссияAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowRussian Federation200903062014114ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XI No 4–2009103109Copyright © Ульянкина И.В., Резник О.Н., Мойсюк Я.Г., 20092009Ульянкина И.В., Резник О.Н., Мойсюк Я.Г.Ulyankina I.V., Reznik O.N., Moysyuk Y.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/277

В статье приводятся данные об обосновании особых схем иммуносупрессии у пациентов, получивших почечный трансплантат от доноров с расширенными критериями. Особое внимание уделяется аспек- там снижения доз ингибиторов кальциневрина у пациентов старшей возрастной группы. Анализируются данные литературы об использовании иммуносупрессии с применением ингибиторов пролиферативного сигнала у пациентов, получивших субоптимальные трансплантаты почек. 

The article reflects the use of special schemes of immunosupression in recipients who received kidneys from expanded criteria donors. The reduction of traditional doses of cyclosporine A is discussed in old patients. The data of literature is reviewed about immunosupression schemes including inhibitors of proliferative signal, especially everolimus. 

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The authors declare that there are no conflicts of interest present.