References

vtio

Вестник трансплантологии и искусственных органов

Russian Journal of Transplantology and Artificial Organs

1995-1191

Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation

10.15825/1995-1191-2009-3-17-29

vtio-241

Research Article

Клиническая трансплантология

Clinical Transplantology

РЕАБИЛИТАЦИЯ ДОНОРСКИХ ОРГАНОВ. НАПРАВЛЕНИЕ В КОНСЕРВАЦИИ ИЛИ НОВАЯ ПАРАДИГМА ТРАНСПЛАНТОЛОГИИ?

REHABILITATION OF ORGAN FROM DECEASED DONORS. NEW PRESERVATION TREND OR NEW PARADIGM IN TRANSPLANTOLOGY?

Багненко

С. Ф.

Bagnenko

S. F.

Мойсюк

Я. Г.

Moysyuk

Y. G.

Скворцов

А. Е.

Skvortsov

A. E.

Резник

О. Н.

Reznik

O. N.

onreznik@yahoo.com

ГУ «Санкт-Петербургский научно-исследовательский институт им И.И. Джанелидзе», Санкт- ПетербургРоссияState Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgRussian Federation

ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, МоскваРоссияAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowRussian Federation

2009

03062014

113

ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XI No 3–2009

1729

2009

Багненко С.Ф., Мойсюк Я.Г., Скворцов А.Е., Резник О.Н.

Bagnenko S.F., Moysyuk Y.G., Skvortsov A.E., Reznik O.N.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.transpl.ru/vtio/article/view/241

В статье анализируются причины дефицита донорских органов, определяются перспективы расширения донорского пула за счет расширения критериев приемлемости. Подробно освящается роль ишемии-ре- перфузии в трансплантации органов, описываются принятые стратегии редукции последствий ишеми- чески-реперфузионной травмы донорских органов, приводятся обширные литературные данные о роли перфузионных методов консервации в современной трансплантации органов. В статье обосновывается необходимость влияния на качество донорского органа до осуществления трансплантации, дается ряд те- оретических положений изменения практики консервации органов для обеспечения доступности транс- плантации населению.

The articleis is dedicated to the main problem of transplantology which is shortage of acceptable donors’ organs. The tendency of expanding the donor’s pool should include policy of prevention and reduction the ischemia- reperfusion trauma of donor’s organs. The crucial role of machine perfusion in pretransplantaion improving organs quality is highlighted. The large review of literature is listed in order to state several new approaches in modern preservation trend. The definition of organ preservation is given as well as new strategy in organ acceptance is grounded.

доноры с расширенными критериямиишемия-реперфузияаппаратная перфузия донорских органов

expanded criteria donorsischemia-reperfusionmachine perfusion

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The authors declare that there are no conflicts of interest present.