vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2012-4-93-102vtio-225Research ArticleОбзор литературыLiterature ReviewsРАННЯЯ ДИСФУНКЦИЯ ТРАНСПЛАНТАТА И ОСТРОЕ ПОВРЕЖДЕНИЕ ПОЧЕК ПОСЛЕ ТРАНСПЛАНТАЦИИ ПЕЧЕНИ: ОПРЕДЕЛЕНИЯ, ФАКТОРЫ РИСКА И КЛИНИЧЕСКОЕ ЗНАЧЕНИЕEARLY ALLOGRAFT DYSFUNCTION AND ACUTE KIDNEY INJURY AFTER LIVER TRANSPLANTATION: DEFINITIONS, RISK FACTORS AND CLINICAL SIGNIFICANCEМойсюкЛ. Я.MoysyukL. Y.

 

ПопцовВ. Н.PoptsovV. N.МойсюкЯ. Г.MoysyukY. G.ФГБУ «ФНЦ трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России, ГБОУ ВПО «Первый МГМУ имени И.М. Сеченова», кафедра трансплантологии и искусственных органов, г. МоскваРоссияAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organsRussian Federation201229052014144ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XIV No 4–201293102Copyright © Мойсюк Л.Я., Попцов В.Н., Мойсюк Я.Г., 20122012Мойсюк Л.Я., Попцов В.Н., Мойсюк Я.Г.Moysyuk L.Y., Poptsov V.N., Moysyuk Y.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/225

В обзоре обсуждаются вопросы, которые относятся к интенсивной терапии у реципиентов пересаженной печени в раннем послеоперационном периоде с акцентом на современных условиях и подходах, специ- фичных для данной группы пациентов. Ранняя дисфункция трансплантата (РДТ) требует немедленной диагностики и соответствующего лечения. Рассматриваются современное определение РДТ, дифферен- циальная диагностика, обсуждается лечебная тактика. Острое повреждение почек (ОПП) и почечная не- достаточность характерны для пациентов после трансплантации печени. Рассмотрены этиология, факто- ры риска, диагностика и принципы лечения ОПП. Демонстрируется негативное влияние РДТ и ОПП на выживаемость трансплантатов и реципиентов. 

This review discusses issues related to intensive care in recipients of transplanted liver in the early postoperative period, with an emphasis on contemporary conditions and attitudes that are specific for this group of patients. Early allograft dysfunction (EAD) requires immediate diagnosis and appropriate treatment in case. The causes of the EAD and therapeutic tactics are discussed. Acute kidney injury (AKI) and renal failure are common in patients after transplantation. We consider etiology, risk factors, diagnosis and treatment guidelines for AKI. The negative impact of EAD and AKI on the grafts survival and recipients is demonstrated. 

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The authors declare that there are no conflicts of interest present.