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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2012-4-89-92</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-222</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинические наблюдения</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Cases</subject></subj-group></article-categories><title-group><article-title>МАССИВНАЯ ПРОДЛЕННАЯ ПОЛИУРИЯ ПОСЛЕ ТРАНСПЛАНТАЦИИ ПОЧКИ</article-title><trans-title-group xml:lang="en"><trans-title>PROLONGED MASSIVE POLYURIA AFTER RENAL TRANSPLANTATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернявский</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernyavskiy</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpenko</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомичев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomichev</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Едемский</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Edemskiy</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дерягин</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Deryagin</surname><given-names>M. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «ННИИПК им. акад. Е.Н. Мешалкина» Минздравсоцразвития России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care &amp; Social Development RF</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>29</day><month>05</month><year>2014</year></pub-date><volume>14</volume><issue>4</issue><issue-title>ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XIV No 4–2012</issue-title><fpage>89</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чернявский А.М., Карпенко И.В., Фомичев А.В., Едемский А.Г., Дерягин М.Н., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Чернявский А.М., Карпенко И.В., Фомичев А.В., Едемский А.Г., Дерягин М.Н.</copyright-holder><copyright-holder xml:lang="en">Chernyavskiy A.M., Karpenko I.V., Fomichev A.V., Edemskiy A.G., Deryagin M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/222">https://journal.transpl.ru/vtio/article/view/222</self-uri><abstract><p>В статье представлен клинический случай успешного излечения массивной продленной полиурии у па- циентки после аллотрансплантации трупной почки. Полиурия длилась 40 дней, наибольший объем диу- реза достигал 55 литров в сутки. Анализ биоптата трансплантата выявил признаки острого канальцевого некроза, исходного артериосклероза, выставлено подозрение на острое отторжение.Ультразвуковое ис- следование и перфузионная сцинтиграфия трансплантата патологии не выявили. Исходно выполнялись попытки снижения объема внутривенной инфузии и выпиваемой жидкости, проводилась пульс-терапия метипредом. Однако перечисленные мероприятия оказались неэффективными. Стабилизации состояния удалось достичь лишь назначением больших доз препарата антидиуретического гормона минирина. Па- циентка выписана из клиники через 42 дня после операции в удовлетворительном состоянии с хорошей функцией трансплантата. </p></abstract><trans-abstract xml:lang="en"><p>Clinical case of prolonged massive polyuria in patient after renal transplantation is represented in this article. Polyuria lasted for a forty days after kidney transplantation, the larges amount of urine output was 55 litres per day. Analysis of transplant biopsy revealed acute tubular necrosis, initial arteriolosclerosis and suspected acute rejection. Doppler ultrasound study and perfusion scintigraphy detected no pathology. At first we tried to decrease the volume of infusion and fluid intake. Also we performed pulse therapy with methylprednisolone. However, these efforts were not effective. Using of a large doses of «Minerin» (posterior pituitary antidiuretic factor) allowed to decrease and stabilize the volume of urine output. The patient was discharge from clinic on day 42 after transplantation. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиурия</kwd><kwd>трансплантация почки</kwd><kwd>канальцевый некроз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polyuria</kwd><kwd>kidney transplantation</kwd><kwd>tubular necrosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каабак М.М., Соловьева И.Н., Горяйнов В.А. Лече- ние реперфузионного синдрома при трансплантации почки путем проведения плазмафереза // Нефроло- гия и диализ. 2002. Т. 4. No 2.</mixed-citation><mixed-citation xml:lang="en">Каабак М.М., Соловьева И.Н., Горяйнов В.А. Лече- ние реперфузионного синдрома при трансплантации почки путем проведения плазмафереза // Нефроло- гия и диализ. 2002. Т. 4. 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