vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2025-3-46-54vtio-1916Research ArticleКЛИНИЧЕСКАЯ ТРАНСПЛАНТОЛОГИЯCLINICAL TRANSPLANTOLOGYПрименение протоколов ускоренного восстановления после хирургического вмешательства (ERAS) в трансплантации печениImplementation of enhanced recovery after surgery (ERAS) protocols in liver transplantationhttps://orcid.org/0000-0001-5830-5235СемашК. О.SemashK. O.

Семаш Константин Олесьевич.

100171, Ташкент, Яшнабадский р-н, ул. Паркентская, д. 294

Тел. +998 (94) 090-89-05

Konstantin O. Semash.

294, Parkenskaya str., Yashnobod District, Tashkent, 100171

Phone: +998 (94) 090-89-05

mail@doctorsemash.comhttps://orcid.org/0000-0002-8857-947XДжанбековТ. А.DzhanbekovT. A.

Джанбеков Тимур Айдарбекович.

Ташкент

Tashkent

house-md@mail.ruhttps://orcid.org/0000-0002-1365-9125НасыровМ. М.NasyrovM. M.

Насыров Мансур Мухторович.

Ташкент

Tashkent

mansoornasyrov@gmail.comhttps://orcid.org/0009-0005-0809-1511СабировД. Р.SabirovD. R.

Сабиров Джахонгир Рузиевич.

Ташкент

Tashkent

gocjahongir@gmail.comНациональный детский медицинский центрУзбекистанNational Children’s Medical CenterUzbekistan2025030920252734654Copyright © Семаш К.О., Джанбеков Т.А., Насыров М.М., Сабиров Д.Р., 20252025Семаш К.О., Джанбеков Т.А., Насыров М.М., Сабиров Д.Р.Semash K.O., Dzhanbekov T.A., Nasyrov M.M., Sabirov D.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1916

Введение. Трудности, связанные с предоперационной подготовкой, самой операцией и послеоперационной реабилитацией, делают трансплантацию печени одним из самых сложных хирургических вмешательств как с технической, так и с логистической точки зрения. Внедрение протоколов ускоренного восстановления после хирургических операций (ERAS) революционизировало периоперационную помощь в различных хирургических специальностях, значительно улучшив результаты лечения и снизив затраты на здравоохранение. Использование протоколов ERAS у реципиентов печени является редким явлением, характеризующимся значительной вариабельностью подходов между учреждениями. Целью написания данного обзора являлись обобщения знаний и описание текущего статуса развития направления ускоренного восстановления после хирургических операций по протоколам ERAS у реципиентов печени. Материалы и методы. Был проведен поиск научной литературы по ключевым словам: ERAS, LIVER TRANSPLANTATION. В обзор включены источники по релевантной тематике, среди которых были обзорные статьи, клинические испытания, обсервационные исследования и исследования «случай–контроль». Заключение. Протоколы ERAS в трансплантации печени направлены на оптимизацию восстановления, улучшение результатов и снижение риска развития осложнений. Каждый случай трансплантации печени уникален, и протоколы ERAS должны быть адаптированы с учетом состояния пациента, характеристик донора и особенностей самой операции.

Background. Liver transplantation (LT) is one of the most complex surgical procedures, presenting significant challenges in preoperative preparation, intraoperative management, and postoperative rehabilitation. These complexities make it demanding both technically and logistically. The introduction of enhanced recovery after surgery (ERAS) protocols has revolutionized perioperative care across numerous surgical disciplines, leading to improved patient outcomes and reduced healthcare costs. However, the application of ERAS protocols in LT remains limited and inconsistent, with considerable variation in implementation strategies across institutions. Objective: to summarize current knowledge and assess an overview of implementation and outcomes of ERAS protocols in LT recipients. Materials and methods. A structured literature search was conducted using the keywords «ERAS» and «liver transplantation» across major scientific databases. The review included a range of relevant publications, including review articles, clinical trials, observational studies, and case-control studies. Conclusion. ERAS protocols in LT are designed to optimize postoperative recovery, improve clinical outcomes, and minimize the risk of complications. Given the complexity and individuality of each LT case, ERAS pathways must be carefully tailored to the recipient’s clinical condition, donor characteristics, and intraoperative variables.

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The authors declare that there are no conflicts of interest present.