vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2024-3-117-123vtio-1823Research ArticleКлиническая трансплантологияClinical TransplantologyФункциональные показатели жесткости стенки периферических артерий у реципиентов солидных органов (обзор литературы)Functional indicators of peripheral arterial stiffness in solid organ recipients (literature review)ЛысенкоМ. М.LysenkoM. M.

Лысенко Мария Магомедрасуловна - врач функциональной диагностики

Отделение ультразвуковой и функциональной диагностики

123182, Москва, ул. Щукинская, д. 1

 

Mariia М. Lysenko

1, Shchukinskaya str., Moscow, 123182

maria4573@yandex.ruТюняеваИ. Ю.TyunyaevaI. Yu.

Москва

Moscow

ШевченкоА. О.ShevchenkoA. O.

Москва

Moscow

ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияShumakov National Medical Research Center of Transplantology and Artificial OrgansRussian FederationФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России; ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Минздрава России (Сеченовский университет); ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава РоссииРоссияShumakov National Medical Research Center of Transplantology and Artificial Organs; Sechenov University; Pirogov Russian National Research Medical UniversityRussian Federation202403072024263117123Copyright © Лысенко М.М., Тюняева И.Ю., Шевченко А.О., 20242024Лысенко М.М., Тюняева И.Ю., Шевченко А.О.Lysenko M.M., Tyunyaeva I.Y., Shevchenko A.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1823

Высокая артериальная жесткость (ригидность) является важным доклиническим индикатором нарушения функции сердечно-сосудистой системы, развития артериальной гипертензии и поражения органов-мише- ней, а также увеличивает риск развития отдаленных неблагоприятных событий. Реципиенты солидных органов сталкиваются с множественными факторами риска развития осложнений со стороны сердечно- сосудистой системы в связи с отторжением трансплантата, пожизненным приемом лекарственных препа- ратов и адаптационными особенностями функционирования пересаженного органа. В обзоре представлен анализ результатов исследований, посвященных основным функциональным показателям ригидности периферических артерий, а также потенциальному влиянию иммуносупрессивной терапии у реципиентов солидных органов на показатели ригидности сосудистой стенки.

Increased arterial stiffness is an important preclinical indicator of cardiovascular dysfunction, arterial hypertension and target organ injury. This condition increases the risk of long-term adverse events. Solid organ recipients face multiple risk factors for cardiovascular complications due to transplant rejection, lifelong medication use and adaptive features of the transplanted organ. The review presents an analysis of the results of studies on the main functional indicators of peripheral arterial stiffness, as well as the potential effect of immunosuppressive therapy on indicators of vascular stiffness in solid organ recipients.

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The authors declare that there are no conflicts of interest present.