vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2025-1-23-31vtio-1779Research ArticleКлиническая трансплантологияClinical TransplantologyНеблагоприятные эффекты иммуносупрессивной терапии после пересадки почкиAdverse effects of immunosuppressive therapy after kidney transplantПоповС. В.PopovS. V.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

info@lucaclinic.ruГусейновР. Г.GuseinovR. G.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

info@lucaclinic.ruСивакК. В.SivakK. V.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

kvsivak@gmail.comПерепелицаВ. В.PerepelitsaV. V.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

perepelitsa_vit@mail.ruШмидтИ. И.SchmidtI. O.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

info@lucaclinic.ruБуненковН. С.BunenkovN. S.

6, Dekabristov str., Strelna, 198515, St. Petersburg 

bunenkov2006@gmail.comЛелявинаТ. А.LelyavinaT. A.

Лелявина Татьяна Александровна 

198515, Санкт-Петербург, п. Стрельна, ул. Декабристов, д. 6. Тел. (981) 908-90-18 

6, Dekabristov str., Strelna, 198515, St. Petersburg 

tatianalelyavina@mail.ruСПб ГБУЗ «Клиническая больница Святителя Луки» ; ЧОУВО «Санкт-Петербургский медико-социальный институт» ; ФГБВОУ ВО «Военно-медицинская академия имени С.М. Кирова»РоссияSt. Luke’s Clinical Hospital ; St. Petersburg Medico-Social Institute ; Kirov Military Medical AcademyRussian FederationСПб ГБУЗ «Клиническая больница Святителя Луки» ; ЧОУВО «Санкт-Петербургский медико-социальный институт» ; ФГБОУ ВО «Санкт-Петербургский государственный университет»РоссияSt. Luke’s Clinical Hospital ; St. Petersburg Medico-Social Institute ; St. Petersburg State UniversityRussian FederationПб ГБУЗ «Клиническая больница Святителя Луки» ; ФГБУ «Научно-исследовательский институт гриппа имени А.А. Смородинцева» Минздрава РоссииРоссияSt. Luke’s Clinical Hospital ; Smorodintsev Research Institute of InfluenzaRussian FederationСПб ГБУЗ «Клиническая больница Святителя Луки» ; ЧОУВО «Санкт-Петербургский медико-социальный институт»РоссияSt. Luke’s Clinical Hospital ; St. Petersburg Medico-Social InstituteRussian FederationСПб ГБУЗ «Клиническая больница Святителя Луки»РоссияSt. Luke’s Clinical HospitalRussian FederationФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова» Минздрава РоссииРоссияSt. Luke’s Clinical Hospital ; Pavlov UniversityRussian FederationСПб ГБУЗ «Клиническая больница Святителя Луки» ; ФГБУ «Национальный медицинский исследовательский центр имени В.А. Алмазова» Минздрава РоссииРоссияSt. Luke’s Clinical Hospital ; Almazov National Medical Research CentreRussian Federation2025260320252712331Copyright © Попов С.В., Гусейнов Р.Г., Сивак К.В., Перепелица В.В., Шмидт И.И., Буненков Н.С., Лелявина Т.А., 20252025Попов С.В., Гусейнов Р.Г., Сивак К.В., Перепелица В.В., Шмидт И.И., Буненков Н.С., Лелявина Т.А.Popov S.V., Guseinov R.G., Sivak K.V., Perepelitsa V.V., Schmidt I.O., Bunenkov N.S., Lelyavina T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1779

В работе приведен результат изучения источников и обобщение информации о неблагоприятных эффектах иммуносупрессивной терапии, которые играют важную роль в полноценном функционировании трансплантата. В статье показана важность динамического влияния иммуносупрессивной терапии на функционирование трансплантата, необходимость разумного подбора режима и дозировки конкретного лекарственного средства или их комбинации для минимизации неблагоприятных эффектов.

This paper reviews the sources and generality of knowledge regarding the adverse effects of immunosuppressive therapy, which play an important role in the full functioning of a transplant. The article regarding the importance of the dynamic impact of immunosuppressant medications on transplant function and the need for reasonable regimen and dosage selection of individual drugs or their combination to minimize adverse effects.

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The authors declare that there are no conflicts of interest present.