vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2023-2-49-56vtio-1612Research ArticleТрансплантация сердца и вспомогательное кровообращениеHeart Transplantation and Assisted CirculationБивентрикулярная механическая поддержка сердца. История и современное состояние проблемыBiventricular mechanical circulatory support. History and current state of the problemЖульковМ. О.ZhulkovM. O.

Максим Олегович Жульков - кандидат медицинских наук, научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения.

Новосибирск

Novosibirsk

medicus-maligna@mail.ruСиротаД. А.SirotaD. A.

Дмитрий Андреевич Сирота - кандидат медицинских наук, заведующий научно-исследовательским отделом хирургии аорты, коронарных и периферических артерий института патологии кровообращения.

Новосибирск

Novosibirsk

d_sirota@meshalkin.ruХванД. С.KhvanD. S.

Дмитрий Сергеевич Хван - кандидат медицинских наук, старший научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения.

Новосибирск

Novosibirsk

d_hvan@meshalkin.ruМакаевА. Г.MakaevA. G.

Макаев Александр Геннадьевич - ординатор направления сердечно-сосудистая хирургия.

630055, Новосибирск, ул. Речкуновская, д. 15. Тел. (905) 198-33-31

Alexander Makaev

15, Rechkunovskaya str., Novosibirsk, 630055, Russian Federation. Phone: (905) 198-33-31

sashamakaev@mail.ruАгаеваХ. А.AgaevaH. A.

Хава Абдуллаевна Агаева - младший научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения.

Новосибирск

Novosibirsk

agaeva_k@meshalkin.ruЗыковИ. С.ZykovI. S.

Илья Сергеевич Зыков - врач-анестезиолог-реаниматолог отделение анестезиологии-реанимации.

Новосибирск

Novosibirsk

i_zykov@meshalkin.ruФомичевА. В.FomichevA. V.

Алексей Вячеславович Фомичев - кандидат медицинских наук, старший научный сотрудник научно-исследовательского отдела хирургии аорты, коронарных и периферических артерий института патологии кровообращения.

Новосибирск

Novosibirsk

a_fomichev@meshalkin.ruПовещенкоО. В.PoveschenkoO. V.

Ольга Владимировна Повещенко - доктор медицинских наук, заведующая лабораторией клеточных технологий.

Новосибирск

Novosibirsk

poveschenkoov@yandex.ruСуровцеваМ. А.SurovtsevaM. A.

Мария Александровна Суровцева - кандидат медицинских наук, старший научный сотрудник лаборатории клеточных технологий.

Новосибирск

Novosibirsk

mfelde@ngs.ruЧернявскийА. М.ChernyavskyA. M.

Александр Михайлович Чернявский - член корреспондент РАН, доктор медицинских наук, профессор, директор.

Новосибирск

Novosibirsk

amchern@mail.ruФГБУ «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Минздрава РоссииРоссияMeshalkin National Medical Research CenterRussian Federation2023150720232524956Copyright © Жульков М.О., Сирота Д.А., Хван Д.С., Макаев А.Г., Агаева Х.А., Зыков И.С., Фомичев А.В., Повещенко О.В., Суровцева М.А., Чернявский А.М., 20232023Жульков М.О., Сирота Д.А., Хван Д.С., Макаев А.Г., Агаева Х.А., Зыков И.С., Фомичев А.В., Повещенко О.В., Суровцева М.А., Чернявский А.М.Zhulkov M.O., Sirota D.A., Khvan D.S., Makaev A.G., Agaeva H.A., Zykov I.S., Fomichev A.V., Poveschenko O.V., Surovtseva M.A., Chernyavsky A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1612

Медикаментозное лечение терминальной стадии хронической сердечной недостаточности значительно эволюционировало за последние несколько десятилетий. Благодаря лучшему пониманию патофизиологии сердечной недостаточности были синтезированы новые фармакологические агенты. Однако выживаемость при медикаментозном лечении данной когорты пациентов остается крайне низкой, что стимулирует развитие хирургических методов лечения. Последние технологические достижения в разработке устройств механической поддержки сердца сделали возможной одномоментную имплантацию двух центробежных насосов в качестве альтернативы полностью искусственному сердцу. На сегодняшний день вспомогательные желудочковые устройства могут быть имплантированы для обеспечения как унивентрикулярной, так и бивентрикулярной поддержки в зависимости от тяжести гемодинамических нарушений, поражения органов-мишеней, вероятности выздоровления и пересадки сердца.

Medical management of end-stage chronic heart failure (HF) has evolved significantly over the past few decades. With a better understanding of the pathophysiology of HF, new pharmacological agents have been synthesized. However, survival in this cohort of patients with medical treatment remains extremely low. This has stimulated the development of surgical methods of treatment. Recent technological advances in the development of mechanical circulatory assist devices have made possible a single-stage implantation of two centrifugal pumps as an alternative to a total artificial heart. Today ventricular assist devices can be implanted to provide both univentricular and biventricular support depending on the severity of hemodynamic disorders, target organ damage, likelihood of recovery and heart transplantation.

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The authors declare that there are no conflicts of interest present.