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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2022-3-57-63</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-1533</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая трансплантология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Transplantology</subject></subj-group></article-categories><title-group><article-title>Ранняя диагностика и лечение синдрома обкрадывания селезеночной артерией после трансплантации печени</article-title><trans-title-group xml:lang="en"><trans-title>Early diagnosis and treatment of splenic artery steal syndrome after liver transplantation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киршин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirshin</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Киршин Александр Александрович</p><p>Адрес: 420064, Казань, ул. Б. Урманче, 10-222Тел. (912) 467-52-79</p></bio><bio xml:lang="en"><p>Alexandr Kirshin</p><p>Address: 10-222, B. Urmanche str., Kazan, 420064Phone: (912) 467-52-79</p></bio><email xlink:type="simple">kirshinalex80@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терегулов</surname><given-names>A. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Teregulov</surname><given-names>А. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казань</p></bio><bio xml:lang="en"><p>Kazan</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киршина</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirshina</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казань</p></bio><bio xml:lang="en"><p>Kazan</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГАУЗ «Республиканская клиническая больница» Минздрава Республики Татарстан; Институт фундаментальной медицины и биологии Казанского федерального университета</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Clinical Hospital; Kazan Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГАУЗ «Республиканская клиническая больница» Минздрава Республики Татарстан</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>23</day><month>08</month><year>2022</year></pub-date><volume>24</volume><issue>3</issue><fpage>57</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Киршин А.А., Терегулов A.Ю., Киршина А.Р., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Киршин А.А., Терегулов A.Ю., Киршина А.Р.</copyright-holder><copyright-holder xml:lang="en">Kirshin А.А., Teregulov А.Y., Kirshina A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/1533">https://journal.transpl.ru/vtio/article/view/1533</self-uri><abstract><p>Цель исследования. Изучить частоту возникновения синдрома обкрадывания селезеночной артерией в собственной серии трансплантаций печени с определением диагностической и лечебной тактики. Материалы и методы. За 3,5 года существования программы трансплантации печени в Республике Татарстан выполнено 77 трансплантаций трупной печени. В послеоперационном периоде синдром обкрадывания селезеночной артерией встретился в 4 случаях (5,2%). Среди пациентов было 3 женщины и один мужчина, средний возраст составил 38 лет. Для диагностики применялись ультразвуковая доплерография сосудов печени и целиакография. В качестве способа коррекции синдрома использовалась проксимальная эмболизация селезеночной артерии. Результаты. Во всех клинических наблюдениях синдром обкрадывания селезеночной артерией был своевременно диагностирован и корректирован посредством рентгенэндоваскулярного вмешательства. Пациенты выписаны с хорошей функцией печеночного графта. Осложнение не повлияло на продолжительность госпитализации. Заключение. Синдром обкрадывания селезеночной артерией остается серьезным сосудистым осложнением трансплантации печени, способным привести к дисфункции и возможной потере графта. Его своевременное выявление и коррекция предотвращают тяжелые последствия для реципиента печени.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to study the incidence of splenic artery steal syndrome (SASS) in our own series of liver transplant surgeries and to determine diagnostic and therapeutic tactics. Materials and Methods. During the 3.5 years of existence of the liver transplant program in the Republic of Tatarstan, 77 cadaveric liver transplantations (LTx) have been performed. Postoperative SASS occurred in 4 cases (5.2%). Among the patients were 3 women and 1 man; mean age was 38 years. Doppler ultrasonography of the liver vessels and celiacography were used for diagnosis. Proximal splenic embolization was used as a way to correct the syndrome. Results. In all clinical cases, SASS was timely diagnosed and corrected by endovascular image-guided intervention. The patients were discharged with good hepatic graft function. The complication did not affect the length of hospital stay. Conclusion. SASS remains a severe vascular complication of LTx, which can lead to graft dysfunction and possible loss. Timely detection and treatment prevent severe consequences for the liver recipient.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация печени</kwd><kwd>синдром обкрадывания селезеночной артерией</kwd><kwd>эмболизация селезеночной артерии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver transplantation</kwd><kwd>splenic artery steal syndrome</kwd><kwd>splenic embolization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">De Carlis L, Sansalone CV, Rondinara GF et al. Splenic artery steal syndrome after orthotopic liver transplantation: diagnosis and treatment. Transplant Proc. 1993; 25 (4): 2594–2596.</mixed-citation><mixed-citation xml:lang="en">De Carlis L, Sansalone CV, Rondinara GF et al. Splenic artery steal syndrome after orthotopic liver transplantation: diagnosis and treatment. Transplant Proc. 1993; 25 (4): 2594–2596.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Geissler I, Lamesch P, Witzigmann H, Jost U, Hauss J, Fangmann J. Splenohepatic arterial steal syndrome in liver transplantation: clinical features and management. Transpl Int. 2002; 15 (2–3): 139–141.</mixed-citation><mixed-citation xml:lang="en">Geissler I, Lamesch P, Witzigmann H, Jost U, Hauss J, Fangmann J. Splenohepatic arterial steal syndrome in liver transplantation: clinical features and management. Transpl Int. 2002; 15 (2–3): 139–141.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pinto S, Reddy SN, Horrow MM, Ortiz J. Splenic Artery Syndrome after orthotopic liver transplantation: a review. Int J Surg. 2014; 12 (11): 1228–1234.</mixed-citation><mixed-citation xml:lang="en">Pinto S, Reddy SN, Horrow MM, Ortiz J. Splenic Artery Syndrome after orthotopic liver transplantation: a review. Int J Surg. 2014; 12 (11): 1228–1234.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Uflacker R, Selby JB, Chavin K, Rogers J, Baliga P. Transcatheter splenic artery occlusion for treatment of splenic artery steal syndrome after orthotopic liver transplantation. Cardiovasc Intervent Radiol. 2002; 25 (4): 300–306.</mixed-citation><mixed-citation xml:lang="en">Uflacker R, Selby JB, Chavin K, Rogers J, Baliga P. Transcatheter splenic artery occlusion for treatment of splenic artery steal syndrome after orthotopic liver transplantation. Cardiovasc Intervent Radiol. 2002; 25 (4): 300–306.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Manner M, Otto G, Senninger N, Kraus T, Goerich J, Herfarth C. Arterial steal: an unusual cause for hepatic hypoperfusion after liver transplantation. Transpl Int. 1991; 4: 122–124.</mixed-citation><mixed-citation xml:lang="en">Manner M, Otto G, Senninger N, Kraus T, Goerich J, Herfarth C. Arterial steal: an unusual cause for hepatic hypoperfusion after liver transplantation. Transpl Int. 1991; 4: 122–124.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Quintini C, Hirose K, Hashimoto K, Diago T, Aucejo F, Eghtesad B et al. «Splenic artery steal syndrome» is a misnomer: the cause is portal hyperperfusion, not arterial siphon. Liver Transpl. 2008; 14: 374–379.</mixed-citation><mixed-citation xml:lang="en">Quintini C, Hirose K, Hashimoto K, Diago T, Aucejo F, Eghtesad B et al. «Splenic artery steal syndrome» is a misnomer: the cause is portal hyperperfusion, not arterial siphon. Liver Transpl. 2008; 14: 374–379.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Eipel C, Abshagen K, Vollmar B. Regulation of hepatic blood flow: the hepatic arterial buffer response revisited. World J Gastroenterol. 2010; 16 (48): 6046–6057.</mixed-citation><mixed-citation xml:lang="en">Eipel C, Abshagen K, Vollmar B. Regulation of hepatic blood flow: the hepatic arterial buffer response revisited. World J Gastroenterol. 2010; 16 (48): 6046–6057.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Terra C, Furtado E, Agostinho AG, Donato P. Splenic Artery Steal Syndrome – a Misleading Term: An Independent Artery Origin Supporting Portal Hyperperfusion Theory. Journal of Vascular and Interventional Radiology. 2020; 31 (11): 1916–1918.</mixed-citation><mixed-citation xml:lang="en">Terra C, Furtado E, Agostinho AG, Donato P. Splenic Artery Steal Syndrome – a Misleading Term: An Independent Artery Origin Supporting Portal Hyperperfusion Theory. Journal of Vascular and Interventional Radiology. 2020; 31 (11): 1916–1918.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Saad WEA. Nonocclusive hepatic artery hypoperfusion syndrome (splenic steal syndrome) in liver transplant recipients. Semin Intervent Radiol. 2012; 29: 140–146.</mixed-citation><mixed-citation xml:lang="en">Saad WEA. Nonocclusive hepatic artery hypoperfusion syndrome (splenic steal syndrome) in liver transplant recipients. Semin Intervent Radiol. 2012; 29: 140–146.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nüssler NC, Settmacher U, Haase R, Stange B, Heise M, Neuhaus P. Diagnosis and treatment of arterial steal syndromes in liver transplant recipients. Liver Transpl. 2003; 9 (6): 596–602.</mixed-citation><mixed-citation xml:lang="en">Nüssler NC, Settmacher U, Haase R, Stange B, Heise M, Neuhaus P. Diagnosis and treatment of arterial steal syndromes in liver transplant recipients. Liver Transpl. 2003; 9 (6): 596–602.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Vit A, De Candia A, Como G, Del Frate C, Marzio A, Bazzocchi M. Doppler evaluation of arterial complications of adult orthotopic liver transplantation. J Clin Ultrasound. 2003; 31 (7): 339–345.</mixed-citation><mixed-citation xml:lang="en">Vit A, De Candia A, Como G, Del Frate C, Marzio A, Bazzocchi M. Doppler evaluation of arterial complications of adult orthotopic liver transplantation. J Clin Ultrasound. 2003; 31 (7): 339–345.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kirbas I, Ulu EMK, Ozturk A, Coskun M, Harman A, Ogus E, Haberal M. Multidetector computed tomographic angiography findings of splenic artery steal syndrome in liver transplantation. Transplant Proc. 2007; 39 (4): 1178–1180.</mixed-citation><mixed-citation xml:lang="en">Kirbas I, Ulu EMK, Ozturk A, Coskun M, Harman A, Ogus E, Haberal M. Multidetector computed tomographic angiography findings of splenic artery steal syndrome in liver transplantation. Transplant Proc. 2007; 39 (4): 1178–1180.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Grieser C, Denecke T, Steffen IG et al. Multidetector computed tomography for preoperative assessment of hepatic vasculature and prediction of splenic artery steal syndrome in patients with liver cirrhosis before transplantation. Eur Radiol. 2010; 20 (1): 108–117.</mixed-citation><mixed-citation xml:lang="en">Grieser C, Denecke T, Steffen IG et al. Multidetector computed tomography for preoperative assessment of hepatic vasculature and prediction of splenic artery steal syndrome in patients with liver cirrhosis before transplantation. Eur Radiol. 2010; 20 (1): 108–117.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Dokmak S, Aussilhou B, Belghiti J. Liver transplantation and splenic artery steal syndrome: the diagnosis should be established preoperatively. Liver Transpl. 2013; 19 (6): 667–668.</mixed-citation><mixed-citation xml:lang="en">Dokmak S, Aussilhou B, Belghiti J. Liver transplantation and splenic artery steal syndrome: the diagnosis should be established preoperatively. Liver Transpl. 2013; 19 (6): 667–668.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Madoff DC, Denys A, Wallace MJ, Murthy R, Gupta S, Pillsbury EP et al. Splenic arterial interventions: anatomy, indications, technical considerations, and potential complications. Radiographics. 2005; 25 (Suppl 1): 191– 211.</mixed-citation><mixed-citation xml:lang="en">Madoff DC, Denys A, Wallace MJ, Murthy R, Gupta S, Pillsbury EP et al. Splenic arterial interventions: anatomy, indications, technical considerations, and potential complications. Radiographics. 2005; 25 (Suppl 1): 191– 211.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Fleckenstein FN, Luedemann WM, Kücükkaya A, Auer TA, Plewe J et al. Splenic artery steal syndrome in patients with orthotopic liver transplant: Where to embolize the splenic artery? PLoS One. 2022; 17 (3): e0263832.</mixed-citation><mixed-citation xml:lang="en">Fleckenstein FN, Luedemann WM, Kücükkaya A, Auer TA, Plewe J et al. Splenic artery steal syndrome in patients with orthotopic liver transplant: Where to embolize the splenic artery? PLoS One. 2022; 17 (3): e0263832.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
