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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2022-1-23-30</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-1449</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клиническая трансплантология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Transplantology</subject></subj-group></article-categories><title-group><article-title>История и опыт трансплантации почки в Узбекистане</article-title><trans-title-group xml:lang="en"><trans-title>History and background of kidney transplantation in Uzbekistan</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маткаримов</surname><given-names>З. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Matkarimov</surname><given-names>Z. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маткаримов Зохиджон Турдалиевич</p><p>700138, Ташкент, Учтепинский район, 15-й квартал, д. 21, кв. 17.</p><p>Тел. +998 (90) 995-31-03</p></bio><bio xml:lang="en"><p>Zohidjon Matkarimov</p><p>apt 17, building 21, block 15, Uchtepa District, Tashkent, 700138</p><p>Phone: +998 (90) 995-31-03</p><p> </p></bio><email xlink:type="simple">2dok.mzt@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бахритдинов</surname><given-names>Ф. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Bahritdinov</surname><given-names>F. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибадов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibadov</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суюмов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Suyumov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмудов</surname><given-names>К. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Mahmudov</surname><given-names>Q. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахмедов</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ahmedov</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шерназаров</surname><given-names>Ш. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shernazarov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рустамов</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Rustamov</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдугафуров</surname><given-names>З. У.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdugafurov</surname><given-names>Z. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саатова</surname><given-names>У. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Saatova</surname><given-names>U. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уринов</surname><given-names>Ж. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Urinov</surname><given-names>J. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ташкент</p></bio><bio xml:lang="en"><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «Республиканский специализированный научно-практический медицинский центр хирургии имени академика В. Вахидова»</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Vakhidov Republican Specialized Scientific and Practical Medical Center of Surgery</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>09</day><month>02</month><year>2022</year></pub-date><volume>24</volume><issue>1</issue><fpage>23</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маткаримов З.Т., Бахритдинов Ф.Ш., Ибадов Р.А., Суюмов А.С., Махмудов К.О., Ахмедов А.Р., Шерназаров Ш.И., Рустамов М.О., Абдугафуров З.У., Саатова У.М., Уринов Ж.Б., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Маткаримов З.Т., Бахритдинов Ф.Ш., Ибадов Р.А., Суюмов А.С., Махмудов К.О., Ахмедов А.Р., Шерназаров Ш.И., Рустамов М.О., Абдугафуров З.У., Саатова У.М., Уринов Ж.Б.</copyright-holder><copyright-holder xml:lang="en">Matkarimov Z.T., Bahritdinov F.S., Ibadov R.A., Suyumov A.S., Mahmudov Q.O., Ahmedov A.R., Shernazarov S.I., Rustamov M.O., Abdugafurov Z.U., Saatova U.M., Urinov J.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/1449">https://journal.transpl.ru/vtio/article/view/1449</self-uri><abstract><p>В данной работе представлен краткий очерк истории развития трансплантационной службы в РУз, зародившейся в Центре трансплантации почки АН РУз. Освещена роль выдающихся ученых Узбекистана, их труды и усилия на пути создания отдельного направления клинической и научной медицины в РУз. Показаны достижения научной школы академика АН Республики Узбекистан У.А. Арипова, выполнившего в 1972 г. первую успешную трансплантацию почки. Отражены взлеты и падения отечественной службы трансплантационной нефрологии, а также зарождение отечественной школы трансплантации почки в Государственном учреждении «Республиканский специализированный научно-практический медицинский центр хирургии (РСНПМЦХ) имени академика В. Вахидова» во главе с академиком Ф.Г. Назировым, придавшей стимул «второго дыхания» отечественной трансплантологической школе. Отдельное внимание обращено на актуальные проблемы отечественной трансплантологии, отражены морально-этические и нормативно правовые вопросы, неизбежно сопровождающие указанное научно-клиническое направление. Приведены результаты трансплантации почки в Узбекистане, обозначены перспективы дальнейших научных и клинических направлений.</p></abstract><trans-abstract xml:lang="en"><p>This paper presents a brief outline of the history of transplantation service in the Republic of Uzbekistan, which originated at the country’s Center for Kidney Transplantation. The role played by outstanding scientists in Uzbekistan, their works and efforts towards the creation of a separate area of clinical and scientific medicine in Uzbekistan, are highlighted. Achievements by the research school of U.A. Aripov, Academician of the Academy of Sciences of the Republic of Uzbekistan, who performed the first successful kidney transplantation in 1972, are shown. The ups and downs of national transplantation nephrology, as well as the birth of a national school of kidney transplantation, domiciled at the Vakhidov Republican Specialized Scientific and Practical Medical Center of Surgery, headed by academician F.G. Nazirov, and giving a stimulus to the «second breath» of the national school of transplantology, is reflected. Separate attention is devoted to the actual problems of national transplantology, moral, ethical and regulatory issues that inevitably accompany this scientific and clinical direction are reflected. Kidney transplant outcomes in Uzbekistan are given, the prospects for further scientific and clinical directions are indicated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пересадка почки</kwd><kwd>история трансплантации почки</kwd><kwd>живые родственные доноры</kwd><kwd>иммуносупрессивная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>kidney transplantation</kwd><kwd>kidney transplant history</kwd><kwd>living related donors</kwd><kwd>immunosuppressive therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Parajuli S, Aziz F, Clark DF. 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