vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2013-1-79-88vtio-144Research ArticleКлинические наблюденияClinical CasesПЕРВЫЙ ОТЕЧЕСТВЕННЫЙ ОПЫТ ЗАБРЮШИННОЙ ТРАНСПЛАНТАЦИИ ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ C ФОРМИРОВАНИЕМ ДУОДЕНО-ДУОДЕНОАНАСТОМОЗАFIRST NATIONAL EXPERIENCE OF RETROPERITONEAL PANCREAS TRANSPLANTATION WITH THE FORMATION OF DUODENO-DUODENAL ANASTOMOSISПинчукА. В.PinchukA. V.СторожевР. В.StorozhevR. V.БалкаровА. Г.BalkarovA. G.ДмитриевИ. В.DmitrievI. V.ЛазареваК. Е.LazarevaK. E.МуслимовР. Ш.MuslimovR. S.ПинчукТ. П.PinchukT. P.СелинаИ. Е.SelinaI. E.КудряшоваН. Е.KudryashovaN. E.Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского, г. МоскваN.V. Sklifosovsky Research Institute of Emergency Medicine, Moscow201327052014151ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XV No 1–20137988Copyright © Пинчук А.В., Сторожев Р.В., Балкаров А.Г., Дмитриев И.В., Лазарева К.Е., Муслимов Р.Ш., Пинчук Т.П., Селина И.Е., Кудряшова Н.Е., 20132013Пинчук А.В., Сторожев Р.В., Балкаров А.Г., Дмитриев И.В., Лазарева К.Е., Муслимов Р.Ш., Пинчук Т.П., Селина И.Е., Кудряшова Н.Е.Pinchuk A.V., Storozhev R.V., Balkarov A.G., Dmitriev I.V., Lazareva K.E., Muslimov R.S., Pinchuk T.P., Selina I.E., Kudryashova N.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/144

Сочетанная трансплантация почки и поджелудочной железы (ТП и ПЖ) – метод выбора в лече- нии пациентов, страдающих сахарным диабетом 1-го типа, осложненным терминальной диабе- тической нефропатией, которая позволяет достигнуть инсулинонезависимости, остановить или существенно замедлить развитие вторичных осложнений сахарного диабета. Одним из важней- ших условий успешной трансплантации является адекватное дренирование экзокринного секре- та поджелудочной железы. В статье описан первый отечественный опыт забрюшинной сочетан- ной ТП и ПЖ с ретроперитонеальным формированием дуодено-дуоденоанастомоза. 

Simultaneous pancreas-kidney transplantation is a valid therapeutic option for patients with type 1 diabetes mel- litus (DM) and secondary diabetic nephropathy, which enables to achieve an insulin-independent euglycemic state with normalization of glycosylated hemoglobin levels, prevent the secondary complications of diabetes and consequently improve patients, quality of life. There are various transplantation procedures exist. Although pancreas is transplanted because of its endocrine function, one of the main issues, which prevent the successful development of pancreas transplantation, is an exocrine drainage. The aim of this paper was to summarize our first experience of retroperitoneal pancreas transplantation with the formation of duodeno-duodenal anastomosis for enteric drainage. 

сочетанная забрюшинная трансплантация почки и поджелудочной железыдуодено-дуоденоанастомоздренирование экзокринного секретаretroperitoneal pancreas transplantationduodeno-duodenostomyexocrine drainageReferencesRobert J. Corry, R. Shapiro. Pancreatic Transplantati- on // Informa Healthcare. 2007. P. 19–31, 47–55.Robert J. Corry, R. Shapiro. Pancreatic Transplantati- on // Informa Healthcare. 2007. P. 19–31, 47–55.Nadey S. Hakim, Robert J. Stratta, Derek Gray, Peter Friend and Alan Coleman. Pancreas, islet, and stem cell transplantation for diabetes, second edition // Oxford university press. 2010. P. 1–19, 111–137.Nadey S. Hakim, Robert J. Stratta, Derek Gray, Peter Friend and Alan Coleman. Pancreas, islet, and stem cell transplantation for diabetes, second edition // Oxford university press. 2010. P. 1–19, 111–137.Rainer W.G. Gruessner, David E.R. Transplantation of the pancreas // Sutherland. Springer. 2004. P. 39–69, 111–267.Rainer W.G. Gruessner, David E.R. Transplantation of the pancreas // Sutherland. Springer. 2004. P. 39–69, 111–267.Linhares M.M., Beron R.I., Gonzalez A.M. et al. Duode- num-stomach anastomosis: a new technique for exocrine drainage in pancreas transplantation // J. of gastrointesti- nal surgery. 2012. Vol. 16 (5). P. 1072–1075.Linhares M.M., Beron R.I., Gonzalez A.M. et al. Duode- num-stomach anastomosis: a new technique for exocrine drainage in pancreas transplantation // J. of gastrointesti- nal surgery. 2012. Vol. 16 (5). P. 1072–1075.Hummel R., Langer M., Wolters H.H., Senninger N., Brockmann J.G. Exocrine drainage into the duodenum: a novel technique for pancreas transplantation // Trans- plant International. 2008. Vol. 21 (2). P. 178–181.Hummel R., Langer M., Wolters H.H., Senninger N., Brockmann J.G. Exocrine drainage into the duodenum: a novel technique for pancreas transplantation // Trans- plant International. 2008. Vol. 21 (2). P. 178–181.De Roover A., Detry O., Coimbra C., Squifflet J.P., Hono- ré P., Meurisse M. Exocrine pancreas graft drainage in reci- pient duodenum through side-to-side duodeno-duodenos- tomy // Transplant. International. 2008. Vol. 21 (7). P. 707.De Roover A., Detry O., Coimbra C., Squifflet J.P., Hono- ré P., Meurisse M. Exocrine pancreas graft drainage in reci- pient duodenum through side-to-side duodeno-duodenos- tomy // Transplant. International. 2008. Vol. 21 (7). P. 707.Kuo P.C., Johnson L.B., Schweitzer E.J., Bartlett S.T. Si- multaneous pancreas/kidney transplantation-a compari- son of enteric and bladder drainage of exocrine pancre-Kuo P.C., Johnson L.B., Schweitzer E.J., Bartlett S.T. Si- multaneous pancreas/kidney transplantation-a compari- son of enteric and bladder drainage of exocrine pancre-atic secretions // Transplantation. 1997 Jan. Vol. 63 (2).atic secretions // Transplantation. 1997 Jan. Vol. 63 (2).P. 238–243.P. 238–243.Liu B., Ming C.S., Zeng F.J., Sha B., Chen Z.S., Chen Z.H.,Liu B., Ming C.S., Zeng F.J., Sha B., Chen Z.S., Chen Z.H.,Chen S. Simultaneous pancreas-kidney transplantation with modified enteric drainage of exocrine pancreatic secretion // Hepatobiliary and Pancreatic Diseases Inter- national. 2004 May. Vol. 3 (2). P. 183–187.Chen S. Simultaneous pancreas-kidney transplantation with modified enteric drainage of exocrine pancreatic secretion // Hepatobiliary and Pancreatic Diseases Inter- national. 2004 May. Vol. 3 (2). P. 183–187.Ming C., Zeng F., Chen Z. et al. Simultaneous pancreas- kidney transplantation with enteric drainage of exocrine secretions // Chinese Med. J. 2003. Vol. 116 (4). P. 573– 576.Ming C., Zeng F., Chen Z. et al. Simultaneous pancreas- kidney transplantation with enteric drainage of exocrine secretions // Chinese Med. J. 2003. Vol. 116 (4). P. 573– 576.Freund M.C., Steurer W., Gassner E.M. et al. Spectrum of imaging findings after pancreas transplantation with enteric exocrine drainage: Part 1, posttransplantation anatomy // Am. J. of Roentgenology. 2004. Vol. 182 (4). P. 911–917.Freund M.C., Steurer W., Gassner E.M. et al. Spectrum of imaging findings after pancreas transplantation with enteric exocrine drainage: Part 1, posttransplantation anatomy // Am. J. of Roentgenology. 2004. Vol. 182 (4). P. 911–917.Freund M.C., Steurer W., Gassner E.M.et al. Spectrum of imaging findings after pancreas transplantation with en- teric exocrine drainage: Part 2, posttransplantation com- plications // Am. J. of Roentgenology. 2004. Vol. 182 (4). P. 919–925.Freund M.C., Steurer W., Gassner E.M.et al. Spectrum of imaging findings after pancreas transplantation with en- teric exocrine drainage: Part 2, posttransplantation com- plications // Am. J. of Roentgenology. 2004. Vol. 182 (4). P. 919–925.Lall C.G. , Sandrasegaran K., Maglinte D.T., Fridell J.A. Bowel Complications Seen on CT After Pancreas Trans- plantation with Enteric Drainage // Am. J. of Roentgeno- logy. 2006. Vol. 187 (5). P. 1288–1295.Lall C.G. , Sandrasegaran K., Maglinte D.T., Fridell J.A. Bowel Complications Seen on CT After Pancreas Trans- plantation with Enteric Drainage // Am. J. of Roentgeno- logy. 2006. Vol. 187 (5). P. 1288–1295.

The authors declare that there are no conflicts of interest present.