vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/25/1995-1191-2021-4-19-25vtio-1407Research ArticleКлиническая трансплантологияClinical TransplantologyРак легкого у реципиентов солидных органовLung cancer in solid organ transplant recipientsНикулинА. В.NikulinA. V.

Никулин Андрей Владимирович

123182, Москва, ул. Щукинская, д. 1

Тел. (495) 190-35-62

 

Andrey Nikulin

1, Shchukinskaya str., Moscow, 123182, Russian Federation

Phone: (495) 190-35-62

 

nikulin5642@gmail.comПашковИ. В.PashkovI. V.

Москва

Moscow

ЯкунинЯ. С.YakuninYa. S.

Москва

Moscow

ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияShumakov National Medical Research Center of Transplantology and Artificial OrgansRussian Federation2021221020212341925Copyright © Никулин А.В., Пашков И.В., Якунин Я.С., 20222022Никулин А.В., Пашков И.В., Якунин Я.С.Nikulin A.V., Pashkov I.V., Yakunin Y.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1407

Рак легкого остается ведущей причиной смерти в популяции среди всех злокачественных новообразований. Реципиенты солидных органов находятся в группе риска развития злокачественных новообразований, включая рак легкого, за счет длительного приема иммуносупрессивных препаратов. Развитие онкологических заболеваний, включая рак легкого, у этой категории больных отличается рядом особенностей. Кроме того, злокачественные новообразования у реципиентов солидных органов трудно поддаются лечению и имеют худший прогноз. Изучению вопросов, касающихся механизмов развития, методов скрининга и лечения рака легкого у реципиентов солидных органов, посвящен данный обзор.

Lung cancer remains the leading cause of cancer mortality worldwide. Solid organ transplant recipients are at risk of developing malignant tumors, including lung cancer, due to long-term use of immunosuppressive drugs. Development of cancer, including lung cancer, in this patient cohort, has a number of peculiarities. Moreover, malignant tumors in these patients are difficult to treat and have a poorer prognosis. This review presents a study of the issues concerning the mechanisms of lung cancer development, screening methods and treatment in solid organ transplant recipients.

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The authors declare that there are no conflicts of interest present.