vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2013-1-45-50vtio-139Research ArticleКлиническая трансплантологияClinical TransplantologyОЦЕНКА ДИНАМИКИ ФИЗИЧЕСКОЙ РАБОТОСПОСОБНОСТИ ПАЦИЕНТОВ ПОСЛЕ ОРТОТОПИЧЕСКОЙ ТРАНСПЛАНТАЦИИ СЕРДЦА ПО ДАННЫМ СПИРОВЕЛОЭРГОМЕТРИЧЕСКОЙ ПРОБЫ В РАЗЛИЧНЫЕ СРОКИ ПОСЛЕ ОПЕРАЦИИASSESSMENT OF THE DYNAMIC OF PHYSICAL CAPABILITY IN PATIENTS AFTER ORTHOTOPIC HEART TRANSPLANTATION ACCORDING TO BICYCLE ERGOMETRY TEST IN DIFFERENT TERMS AFTER THE OPERATIONСуджаеваО. А.SudzaevaO. A.ОстровскийЮ. П.OstrovskyY. P.Республиканский научно-практический центр «Кардиология», г. Минск, Республика БеларусьRepublican Research and Practice Centre «Cardiology», Minsk, Republic of Belarus201327052014151ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XV No 1–20134550Copyright © Суджаева О.А., Островский Ю.П., 20132013Суджаева О.А., Островский Ю.П.Sudzaeva O.A., Ostrovsky Y.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/139

Цель исследования: оценить динамику физической работоспособности (ФРС) по данным спировелоэр- гометрической пробы в различные сроки после ортотопической трансплатнтации сердца (ОТС). Методы и результаты. У 28 пациентов в возрасте от 19 до 59 лет (в среднем 45,9 ± 2,2 года) динамика показате- лей ФРС оценивалась в срок от 14 до 36 месяцев (в среднем 20,8 ± 1,6 месяца) после ОТС. До операции у всех 28 пациентов имела место низкая толерантность к физической нагрузке (ТФН), а также низкое максимальное потребление кислорода (VO2max). Через 6 и 12 месяцев после ОТС отмечался достоверный рост ТФН и VO2max в сравнении с исходным уровнем (р < 0,05), в более поздние сроки наметилась тен- денция к снижению показателей ФРС в сравнении с выявленными через 6 и 12 месяцев после ОТС, у 3 (20%) из 15 обследованных появилась ишемия миокарда. Заключение. Выявленное снижение ФРС через 14–36 месяцев после ОТС может свидетельствовать о развитии васкулопатии или о прогрессировании исходно имевшегося атеросклеротического процесса. 

Aim. To evaluate dynamic of physical capability (PC) based on bicycle ergometry test data in different post- operation terms after orthotopic heart transplantation (OHT). Methods and results. In 28 patients aged from 19 to 59 (mean 45,9 ± 2,2) years the dynamics of PC values was assessed at 14–36 (mean 20,8 ± 1,6) months after OHT. Prior to surgery, all 28 patients had low exercise tolerance (ET) as well as low maximal oxygen consump- tion (VO2max). A significant increase in ET and VO2max was registered in 6 and 12 months after OHT compared to baseline (р < 0,05), a trend to increasing PC values was noted in 6 to 12 months after OHT compared to baseline, 3 (20%) of 15 patients examined showed myocardial ischemia. Conclusion. The PC decrease revealed in 14–36 months after OHT may be indicative of vasculopathy development or progressive underlying athero- sclerotic process. 

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The authors declare that there are no conflicts of interest present.