vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2013-2-148-155vtio-127Research ArticleОбзор литературыLiterature ReviewsИСПОЛЬЗОВАНИЕ БИОПРЕПАРАТОВ В АБДОМИНАЛЬНОЙ ХИРУРГИИ И ТРАНСПЛАНТАЦИИ ПЕЧЕНИTHE USE OF BIOLOGICAL PRODUCTS IN ABDOMINAL SURGERY AND LIVER TRANSPLANTATIONГабриэлянН. И.GabrielyanN. I.АрефьеваЛ. И.ArefievaL. I.ГорскаяЕ. М.GorskayaE. M.КорниловМ. Н.KornilovM. N.МойсюкЯ. Г.MoysyukY. G.ЦирульниковаО. М.TsirulnikovaO. M.ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России (директор – академик РАМН, проф. С.В. Готье), Москва, Российская ФедерацияAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs (Head – academician of RAMSci S.V. Gautier), Moscow, Russian FederationКафедра трансплантологии и искусственных органов (зав. – академик РАМН, проф. С.В. Готье) ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» (ректор – член-корр. РАМН, проф. П.В. Глыбочко), Москва, Российская ФедерацияDepartment of Tansplantology and Artificial organs (Head – academician of RAMSci, prof. S.V. Gautier) I.M. Sechenov First Moscow State Medical University (Rector – corresponding member of RAMSci, prof. P.V. Glybochko), Moscow, Russian Federation201326052014152ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XV No 2–2013148155Copyright © Габриэлян Н.И., Арефьева Л.И., Горская Е.М., Корнилов М.Н., Мойсюк Я.Г., Цирульникова О.М., 20132013Габриэлян Н.И., Арефьева Л.И., Горская Е.М., Корнилов М.Н., Мойсюк Я.Г., Цирульникова О.М.Gabrielyan N.I., Arefieva L.I., Gorskaya E.M., Kornilov M.N., Moysyuk Y.G., Tsirulnikova O.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/127

В статье представлен обзор новых подходов к профилактике инфекционных осложнений бактериаль- ной природы после проведения высокотехнологичных операций в абдоминальной хирургии, прежде всего, трансплантации печени. Обращается внимание на первые положительные результаты рандоми- зированных исследований по использованию биологических препаратов – пробиотиков, пребиотиков и симбиотиков у пациентов после трансплантации печени. Обосновывается перспективность дальнейшей разработки этого вопроса успешными модельными экспериментами на животных и различными опера- тивными вмешательствами в абдоминальной хирургии. 

This article provides an overview of new approaches to the prevention of infectious complications of bacterial nature after the high-technology operations in the abdominal surgery, first of all, after liver transplantation. At- tention is drawn to the first positive results of randomized studies on the use of biological preparations - probi- otics, prebiotics and synbiotics in patients after liver transplantation. The authors prove the prospects of further development of this subject based on successful model experiments on animals and various operational interven- tions in abdominal surgery. 

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The authors declare that there are no conflicts of interest present.