vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2020-3-174-181vtio-1241Research ArticleОбзор литературыLiterature ReviewsСовременные представления о критериях селекции доноров сердцаModern ideas in heart donor selection criteriaТенчуринаЭ. А.TenchurinaE. A.

Тенчурина Эльмира Анвяровна.

Адрес: 125284, Москва, 2-й Боткинский пр-д, 5.

Тел. (967) 113-87-64.

Elmira Tеnchurina.

Address: 5, Vtoroy Botkinsky proyezd, Moscow, 125284, Russian Federation. 

Phone: (967) 113-87-64.

arimle@inbox.ruМининаМ. Г.MininaM. G.

Москва

Moscow

ГБУЗ «Городская клиническая больница имени С.П. Боткина» ДЗМ, Московский городской координационный центр органного донорстваРоссияMoscow Coordinating Center for Organ Donation (Botkin City Clinical Hospital)Russian FederationГБУЗ «Городская клиническая больница имени С.П. Боткина» ДЗМ, Московский городской координационный центр органного донорства; ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияMoscow Coordinating Center for Organ Donation (Botkin City Clinical Hospital); Shumakov National Medical Research Center of Transplantology and Artificial OrgansRussian Federation202006102020223174181Copyright © Тенчурина Э.А., Минина М.Г., 20202020Тенчурина Э.А., Минина М.Г.Tenchurina E.A., Minina M.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1241

При ограниченных возможностях имеющегося донорского пула и одновременно растущих потребностях в трансплантации донорского сердца встает вопрос о расширении критериев отбора донорского сердца, как одного из способов повышения доступности трансплантации органов, и донорского сердца в частности. Использование доноров с расширенными критериями, с одной стороны, позволяет увеличить число трансплантаций и сократить время пребывания в листе ожидания, с другой – повышает риск неблагоприятного исхода трансплантации. Соответственно, доноры высокого риска нуждаются в более тщательной объективной оценке с использованием прогностических моделей, а органы, полученные от доноров с расширенными критериями – в оптимальном подборе пары «донор–реципиент». Анализ мировых и отечественных исследований, приведенный в данном обзоре, раскрывает глубину современной проблемы селекции доноров сердца.

With the limited capacity of the available donor pool and the simultaneously growing demand for heart transplantation, expanding the heart donor selection criteria as one of the ways of increasing the availability of organ transplantation, and particularly donor heart, has become a challenge. On one hand, the use of expanded criteria donors increases the number of transplants and reduces the time spent on the waiting list. On the other hand, however, it increases the risk of adverse transplant outcomes. Accordingly, high-risk donors require a more thorough objective assessment using predictive models, while organs obtained from expanded criteria donors, require optimal selection of a donor-recipient pair. Analysis of global and national studies presented in this review reveals the depth of the current problem of heart donor selection.

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The authors declare that there are no conflicts of interest present.