vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2020-1-16-25vtio-1139Research ArticleКлиническая трансплантологияClinical TransplantologyИзолированный некомпактный миокард левого желудочка сердца: клинико‑морфологическое исследованиеIsolated non-compaction of the left ventricular myocardium: a clinical and morphological studyИльинскийИ. М.IljinskyI. M.

Москва

Moscow

ИвановА. С.IvanovA. S.

Москва

Moscow

МожейкоН. П.MozheikoN. P.

Москва

Moscow

ЛуговскийМ. К.LugovskiyM. K.

Луговский Максим Константинович.

123182, Москва, ул. Щукинская, д. 1.

Lugovskiy Maksim Konstantinovich.

1, Shchukinskaya str., Moscow, 123182

lugovskiymax@gmail.comФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияShumakov National Medical Research Center of Transplantology and Artificial OrgansRussian Federation2020210420202211625Copyright © Ильинский И.М., Иванов А.С., Можейко Н.П., Луговский М.К., 20202020Ильинский И.М., Иванов А.С., Можейко Н.П., Луговский М.К.Iljinsky I.M., Ivanov A.S., Mozheiko N.P., Lugovskiy M.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1139

Изолированный некомпактный миокард левого желудочка (ИНМЛЖ) у взрослых пациентов является редкой формой первичных кардиомиопатий. Известно несколько морфологических исследований этой патологии, при которой была выполнена трансплантация сердца. Целью данной работы является анализ научной литературы и историй болезни пациентов, а также изучение морфологии желудочков сердца с гистологическим исследованием удаленного сердца у пациентов с ИНМЛЖ. Материалы и методы. Проведен анализ литературы и историй болезни трёх пациентов (2 женщины) в возрасте 18, 31 и 1 мужчины 49 лет с ИНМЛЖ. Для проведения гистологического исследования использовали световую микроскопию фиксированного препарата миокарда, окрашенного гематоксилином и эозином. Результаты. При гистологическом исследовании было подтверждено наличие ИНМЛЖ у данных пациентов. Заключение. ИНМЛЖ – редкое заболевание, которое может протекать как бессимптомно, так и являться причиной тяжелой застойной сердечной недостаточности, требующей трансплантации сердца.

Isolated left ventricular noncompaction (LVNC) in adult patients is a rare form of primary cardiomyopathy. There have been several morphological studies of this condition in which a heart transplantation was performed. Objective: to analyze literature and clinical cases of patients with LVNC, macroscopic and histological data of the removed hearts. Materials and methods. At our center three patients (2 women aged 18 and 31, and 1 man aged 49) were morphologically diagnosed with LVNC had a heart transplant. We retrospectively analyzed the clinical, macroscopic and histological data of the removed hearts in these patients and the results of the transplants performed. Light microscopy of a fixed myocardial preparation stained with hematoxylin and eosin was used for histological examination. Results. A histological examination confirmed the presence of LVMI in these patients. Conclusion. LVMI is a rare disease, that can occur asymptomatic or cause severe congestive heart failure, requiring transplantation.

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The authors declare that there are no conflicts of interest present.