<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2019-3-76-83</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-1066</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинические наблюдения</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Cases</subject></subj-group></article-categories><title-group><article-title>Случай успешной ретрансплантации печени у пациента с ранним тромбозом печеночной артерии, осложненным некрозом желчных протоков, сепсисом</article-title><trans-title-group xml:lang="en"><trans-title>A case report of successful liver retransplantation in patient with early hepatic artery thrombosis complicated by bile ducts necrosis and sepsis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гранов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Granov</surname><given-names>D. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поликарпов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Polikarpov</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тилеубергенов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tileubergenov</surname><given-names>I. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуйков</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuikov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жуйков Владимир Николаевич. Адрес: 197758, Санкт-Петербург, ул. Ленинградская, 70. Тел. (965) 033-19-34.</p></bio><bio xml:lang="en"><p>Zhuikov Vladimir Nikolaevich. Address: 70, Lenigradskaya str., St. Petersburg, 197758. Теl. (965) 033-19-34.</p></bio><email xlink:type="simple">zhuikov.v@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Моисеенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moiseenko</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шералиев</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheraliev</surname><given-names>A. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карданова</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kardanova</surname><given-names>I. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Российский научный центр радиологии и хирургических технологий имени академика А.М. Гранова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.M. Granov Russian Scientific Center of Radiology and Surgical Technology of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>21</volume><issue>3</issue><fpage>76</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гранов Д.А., Поликарпов А.А., Тилеубергенов И.И., Жуйков В.Н., Моисеенко А.В., Шералиев А.Р., Карданова И.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Гранов Д.А., Поликарпов А.А., Тилеубергенов И.И., Жуйков В.Н., Моисеенко А.В., Шералиев А.Р., Карданова И.Г.</copyright-holder><copyright-holder xml:lang="en">Granov D.A., Polikarpov A.A., Tileubergenov I.I., Zhuikov V.N., Moiseenko A.V., Sheraliev A.R., Kardanova I.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/1066">https://journal.transpl.ru/vtio/article/view/1066</self-uri><abstract><p>В представленном случае у пациента во время трансплантации печени после завершения этапа артериальной реконструкции выявлен участок диссекции печеночной артерии (ПА). В течение часа в условиях рентгеноперационной произведено стентирование ПА. В раннем послеоперационном периоде при контрольных ангиографических исследованиях выявлены показания к повторному стентированию ПА, а также эмболизации селезеночной артерии с целью устранения синдрома обкрадывания. Через две недели у пациента развился тромбоз ранее установленных стентов, что потребовало аутовенозного протезирования ПА. Несмотря на все примененные способы реваскуляризации, течение заболевания осложнилось формированием холангиогенных абсцессов, развитием сепсиса. Однако использованные методы эндоваскулярной коррекции сосудистых нарушений в сочетании с проведением своевременной интенсивной и антибактериальной терапии согласно результатам микробиологических исследований позволили сохранить удовлетворительно функционирующий трансплантат. После купирования септических осложнений, стабилизации соматического статуса пациента и нормализации клинико-лабораторных показателей успешно выполнена ретрансплантация печени.</p></abstract><trans-abstract xml:lang="en"><p>In this present case report during liver transplantation a patient was developed dissection of hepatic artery (HA) which was noticed after arterial reconstruction step. In one hour after surgery at intervention operating room stent placement of HA was performed. At early postoperative period by hepatic angiography study indicated for a second stent placement of HA, also embolization of splenic artery to treat a steal syndrome. After 2 weeks a patient developed thrombosis of recently placed stents which was required vascular reconstruction of HA by using autovenous graft. The condition complicated by development of a cholangiogenous hepatic abscesses and sepsis despite of all used possible methods of liver graft revascularization. However, used methods of vascular correction, which combined of timely carried out intensive care and antibiotic therapy according microbiology laboratory results allows saving graft function. After treatment of septic complications and patient’s somatic status stabilization and normalization of laboratory results liver retransplantation was performed. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ретрансплантация печени</kwd><kwd>тромбоз печеночной артерии (ПА)</kwd><kwd>стентирование ПА</kwd><kwd>некроз желчных протоков</kwd><kwd>сепсис</kwd><kwd>абсцессы печени</kwd><kwd>синдром обкрадывания селезеночной артерией</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver retransplantation</kwd><kwd>hepatic artery (HA) thrombosis</kwd><kwd>stent placement of HA</kwd><kwd>bile ducts necrosis</kwd><kwd>sepsis</kwd><kwd>hepatic abscesses</kwd><kwd>splenic artery steal syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Koji Umeshita, Yukihiro Inomata, Hiroyuki Furukawa, Mureo Kasahara, Seiji Kawasaki, Eiji Kobayashi, Norihiro Kokudo, Shotaro Sakisaka, Mitsuo Shimada. Liver transplantation in Japan: Registry by the Japanese Liver Transplantation Society. Hepatology research. Nov 2016; 46 (Issue 12): 1171–1186.</mixed-citation><mixed-citation xml:lang="en">Koji Umeshita, Yukihiro Inomata, Hiroyuki Furukawa, Mureo Kasahara, Seiji Kawasaki, Eiji Kobayashi, Norihiro Kokudo, Shotaro Sakisaka, Mitsuo Shimada. Liver transplantation in Japan: Registry by the Japanese Liver Transplantation Society. Hepatology research. Nov 2016; 46 (Issue 12): 1171–1186.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Adam R, Karam V, Delvart V, O’Grady J, Mirza D, Klempnauer J et al. Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR). Journal of hepatology. Sep 2012; 57 (Issue 3): 675–688.</mixed-citation><mixed-citation xml:lang="en">Adam R, Karam V, Delvart V, O’Grady J, Mirza D, Klempnauer J et al. Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR). Journal of hepatology. Sep 2012; 57 (Issue 3): 675–688.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Zarrinpar A, Hong JC. What is the prognosis after retransplantation of the liver? Adv Surg. 2012; 46: 87.</mixed-citation><mixed-citation xml:lang="en">Zarrinpar A, Hong JC. What is the prognosis after retransplantation of the liver? Adv Surg. 2012; 46: 87.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Pfitzmann R, Benscheidt B, Langrehr JM, Schumacher G, Neuhaus R, Neuhaus P. Trends and experiences in liver retransplantation over 15 years. Liver Transplantation. 2007; 13: 248.</mixed-citation><mixed-citation xml:lang="en">Pfitzmann R, Benscheidt B, Langrehr JM, Schumacher G, Neuhaus R, Neuhaus P. Trends and experiences in liver retransplantation over 15 years. Liver Transplantation. 2007; 13: 248.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Azoulay D, Linhares MM, Huguet E, Delvart V, Castaing D, Adam R et al. Decision for retransplantation of the liver. An experience and cost based analysis. Ann Surg. 2002; 236: 713.</mixed-citation><mixed-citation xml:lang="en">Azoulay D, Linhares MM, Huguet E, Delvart V, Castaing D, Adam R et al. Decision for retransplantation of the liver. An experience and cost based analysis. Ann Surg. 2002; 236: 713.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Remiszewski P, Kalinowski P, Dudek K, Grodzicki M, Paluszkiewicz R, Zieniewicz K et al. Influence of selected factors on survival after liver retransplantation. Transplant Proc; 2011; 43: 3025.</mixed-citation><mixed-citation xml:lang="en">Remiszewski P, Kalinowski P, Dudek K, Grodzicki M, Paluszkiewicz R, Zieniewicz K et al. Influence of selected factors on survival after liver retransplantation. Transplant Proc; 2011; 43: 3025.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Pareja E, Cortes M, Navarro R, Sanjuan F, López R, Mir J. Vascular Complications After Orthotopic Liver Transplantation: Hepatic Artery Thrombosis. Transplantation Proceedings. Oct 2010; 42 (Issue 8): 2970–2972.</mixed-citation><mixed-citation xml:lang="en">Pareja E, Cortes M, Navarro R, Sanjuan F, López R, Mir J. Vascular Complications After Orthotopic Liver Transplantation: Hepatic Artery Thrombosis. Transplantation Proceedings. Oct 2010; 42 (Issue 8): 2970–2972.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ashish Singhal, Kenneth Stokes, Anthony Sebastian, Harlan I Wright, Vivek Kohli. Endovascular treatment of hepatic artery thrombosis following liver transplantation. Transplant International. Mar 2010; 23 (Issue 3): 245–256.</mixed-citation><mixed-citation xml:lang="en">Ashish Singhal, Kenneth Stokes, Anthony Sebastian, Harlan I Wright, Vivek Kohli. Endovascular treatment of hepatic artery thrombosis following liver transplantation. Transplant International. Mar 2010; 23 (Issue 3): 245–256.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Scarincia A, Sainz-Barrigaa M, Berrevoeta F, van den Bossche B, Colle I, Geerts A et al. Early Arterial Revascularization After Hepatic Artery Thrombosis May Avoid Graft Loss and Improve Outcomes in Adult Liver Transplantation. Transplantation Proceedings. Dec 2010; 42 (Issue 10): 4403–4408.</mixed-citation><mixed-citation xml:lang="en">Scarincia A, Sainz-Barrigaa M, Berrevoeta F, van den Bossche B, Colle I, Geerts A et al. Early Arterial Revascularization After Hepatic Artery Thrombosis May Avoid Graft Loss and Improve Outcomes in Adult Liver Transplantation. Transplantation Proceedings. Dec 2010; 42 (Issue 10): 4403–4408.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Готье СВ, Мойсюк ЯГ, Попцов ВН, Корнилов МН, Цирульникова ОМ, Ярошенко ЕБ и др. Опыт 100 трансплантаций трупной печени в одном центре. Вестник трансплантологии и искусственных органов. 2012; 14 (1): 6–14. Gautier SV, Moysyuk YaG, Poptsov VN, Kornilov MN, Tsirulnikova OM, Yaroshenko EB et al. One hundred deceased donor liver transplantations at a single center. Russian Journal of Transplantology and Artificial Organs. 2012; 14 (1): 6–14. [In Russ, English abstract].</mixed-citation><mixed-citation xml:lang="en">Готье СВ, Мойсюк ЯГ, Попцов ВН, Корнилов МН, Цирульникова ОМ, Ярошенко ЕБ и др. Опыт 100 трансплантаций трупной печени в одном центре. Вестник трансплантологии и искусственных органов. 2012; 14 (1): 6–14. Gautier SV, Moysyuk YaG, Poptsov VN, Kornilov MN, Tsirulnikova OM, Yaroshenko EB et al. One hundred deceased donor liver transplantations at a single center. Russian Journal of Transplantology and Artificial Organs. 2012; 14 (1): 6–14. [In Russ, English abstract].</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Morell CM, Fabris L, Strazzabosco M. Vascular biology of the biliary epithelium. J Gastroenterol Hepatol. 2013; 28 (1): 26.</mixed-citation><mixed-citation xml:lang="en">Morell CM, Fabris L, Strazzabosco M. Vascular biology of the biliary epithelium. J Gastroenterol Hepatol. 2013; 28 (1): 26.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kawecki D, Chmura A, Pacholczyk M, Lagiewska B, Adadynski L, Wasiak D et al. Bacterial infections in the early period after liver transplantation: etiological agents and their susceptibility. Med Sci Monit. 2009; 15 (12): CR628–CR637.</mixed-citation><mixed-citation xml:lang="en">Kawecki D, Chmura A, Pacholczyk M, Lagiewska B, Adadynski L, Wasiak D et al. Bacterial infections in the early period after liver transplantation: etiological agents and their susceptibility. Med Sci Monit. 2009; 15 (12): CR628–CR637.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Wong T, Devlin J, Rolando N, Heaton N, Williams R. Clinical characteristics affecting the outcome of liver retransplantation. Transplantation. Sep 27th, 1997; 64 (Issue 6): 878–882.</mixed-citation><mixed-citation xml:lang="en">Wong T, Devlin J, Rolando N, Heaton N, Williams R. Clinical characteristics affecting the outcome of liver retransplantation. Transplantation. Sep 27th, 1997; 64 (Issue 6): 878–882.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Гранов АМ, Гранов ДА, Поликарпов АА, Таразов ПГ, Жеребцов ФК, Боровик ВВ и др. Методики интервенционной радиологии в пред- и послеоперационном периоде ортотопической трансплантации печени. Вестник трансплантологии и искуственных органов. 2016; 18: 97. Granov AM, Granov DA, Polikarpov AA, Tarazov PG, Zherebtsov FK, Borovik VV i dr. Metodiki interventsionnoy radiologii v pred- i posleoperatsionnom periode ortotopicheskoy transplantatsii pecheni. Vestnik transplantologii i iskustvennykh organov. 2016; 18: 97.</mixed-citation><mixed-citation xml:lang="en">Гранов АМ, Гранов ДА, Поликарпов АА, Таразов ПГ, Жеребцов ФК, Боровик ВВ и др. Методики интервенционной радиологии в пред- и послеоперационном периоде ортотопической трансплантации печени. Вестник трансплантологии и искуственных органов. 2016; 18: 97. Granov AM, Granov DA, Polikarpov AA, Tarazov PG, Zherebtsov FK, Borovik VV i dr. Metodiki interventsionnoy radiologii v pred- i posleoperatsionnom periode ortotopicheskoy transplantatsii pecheni. Vestnik transplantologii i iskustvennykh organov. 2016; 18: 97.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Masior L, Grąt M, Krasnodębski M, Patkowski W, Figiel W, Bik E, Krawczyk M. Prognostic Factors and Outcomes of Patients After Liver Retransplantation. June 2016; 48 (Issue 5): 1717–1720.</mixed-citation><mixed-citation xml:lang="en">Masior L, Grąt M, Krasnodębski M, Patkowski W, Figiel W, Bik E, Krawczyk M. Prognostic Factors and Outcomes of Patients After Liver Retransplantation. June 2016; 48 (Issue 5): 1717–1720.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kurz P, Kohler H, Meuer S, Hütteroth T, Meyer zum Büschenfelde K et al. Impaired cellular immune responses in chronic renal failure: evidence for a T cell deficit. Kidney Int. 1986; 29: 1209.</mixed-citation><mixed-citation xml:lang="en">Kurz P, Kohler H, Meuer S, Hütteroth T, Meyer zum Büschenfelde K et al. Impaired cellular immune responses in chronic renal failure: evidence for a T cell deficit. Kidney Int. 1986; 29: 1209.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Roughneen PT, Gouma DJ, Kulkarni AD, Fanslow WF, Rowlands B. Impaired specific cell-mediated immunity in experimental biliary obstruction and its reversibility by internal biliary drainage. J Surg Res. 1986; 41: 113.</mixed-citation><mixed-citation xml:lang="en">Roughneen PT, Gouma DJ, Kulkarni AD, Fanslow WF, Rowlands B. Impaired specific cell-mediated immunity in experimental biliary obstruction and its reversibility by internal biliary drainage. J Surg Res. 1986; 41: 113.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Clements WD, Halliday MI, McCaigue MD, Barclay RG, Rowlands BJ. Effects of extrahepatic obstructive jaundice on Kupffer cell clearance capacity. Arch Surg. 1993; 128: 200.</mixed-citation><mixed-citation xml:lang="en">Clements WD, Halliday MI, McCaigue MD, Barclay RG, Rowlands BJ. Effects of extrahepatic obstructive jaundice on Kupffer cell clearance capacity. Arch Surg. 1993; 128: 200.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
