vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2019-3-69-75vtio-1065Research ArticleТрансплантация сердца и вспомогательное кровообращениеHeart Transplantation and Assisted CirculationГемодинамическая оценка нового метода генерации пульсирующего потока в системах сердечно-легочного обходаHemodynamic evaluation of a new pulsatile flow generation method in cardiopulmonary bypass systemБучневА. С.BuchnevA. S.КулешовА. П.KuleshovA. P.ДробышевА. А.DrobyshevA. A.ИткинГ. П.ItkinG. P.

Иткин Георгий Пинкусович. Адрес: 123182, Москва, ул. Щукинская, д. 1. Тел. (499) 190-60-34.

кафедра живых систем

Itkin George Pinkusovich. Address: 1, Shchukinskaya str., Moscow, 123182. Тel. (499) 190-60-34.

Department of physics of living systems

georgeitkin@mail.ruФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationRussian FederationФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России; Московский физико-технический институтРоссияV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation; Moscow Institute of Physics and TechnologyRussian Federation2019300920192136975Copyright © Бучнев А.С., Кулешов А.П., Дробышев А.А., Иткин Г.П., 20192019Бучнев А.С., Кулешов А.П., Дробышев А.А., Иткин Г.П.Buchnev A.S., Kuleshov A.P., Drobyshev A.A., Itkin G.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1065

Предложен новый метод генерации пульсирующего потока с использованием насосов непульсирующего потока (ННП) без модуляции скорости вращения ротора насоса. На начальном этапе данный метод предложен для систем сердечно-легочного обхода (СЛО), построенных на базе ННП. Метод генерации пульсирующего потока основан на параллельном подключении к ННП шунта (вход-выход), на котором установлен управляемый клапан. Данный клапан обеспечивает периодическое частичное пережатие и открытие шунта. Сравнительная оценка работы насосов без пульсатора и с пульсатором проводилась на гидродинамическом стенде с моделированием условий сердечной недостаточности (СН). Система «насос– шунт» подключалась по схеме СЛО «вена–артерия» при работе в режиме сопульсации. В качестве ННП был использован Rotaflow (Maquet Inc.). Для сравнительной оценки гемодинамической эффективности метода использовали: индекс аортальной пульсации Ip, энергию эквивалентного давления (англ. ЕЕР) и избыточную гемодинамическую энергию (англ. SHE). Индексы в пульсирующем режиме по сравнению с непульсирующим режимом увеличились: Iр в 3 раза, индекс ЕЕР на 3,76% и индекс SHE увеличивался в 4 раза. Полученные результаты показывают эффективность предлагаемого метода генерации пульсирующего потока.

This paper proposes a new method of generating pulsatile flow using non-pulsating pumps (NPP) without modulating the rotation speed of the pump rotor. At the initial stage, this method was proposed for NPP-based cardiopulmonary bypass (CPB) systems. The method is based on parallel connection to the NPP shunt (input-output) on which a controlled valve is installed. This valve ensures periodically clamps and opens the shunt partially. A comparative evaluation of the operation of pumps with and without a pulsator was done on a hydrodynamic bench with simulation of heart failure (HF) conditions. The pump-shunt system was connected according to the “veinartery” CPB scheme under copulsation mode. Rotaflow (Maquet Inc.) was used as the NPP. For a comparative assessment of the hemodynamic efficiency of the method, the following were used: aortic pulsatility index Ip, energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). The indices in the pulsating mode compared with the non-pulsating mode increased: Ip by 3 times, EEP index by 3.76% and SHE index increased by 4 times. Results show that the proposed method of generating a pulsating flow is effective.

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The authors declare that there are no conflicts of interest present.