vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2019-1-165-168vtio-1002Research ArticleОбзор литературыLiterature ReviewsВнутрисосудистые методы визуализации в оценке васкулопатии трансплантированного сердцаIntravascular visualization methods in estimating vasculopathy of a transplanted heartСаховскийС. А.SakhovskyS. A.

123182, Москва, ул. Щукинская, д. 1. Тел. (915) 166-56-54.

1, Shchukinskaya str., Moscow, 123182. Тel. (915) 166-56-54.

milifolium@gmail.comКолосковаН. Н.KoloskovaN. N.

Москва

Moscow

ГончароваА. Ю.GoncharovaA. Yu.

Москва

Moscow

МиронковБ. Л.MironkovB. L.

Москва

Moscow

ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияV.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian FederationRussian Federation201918052019211165168Copyright © Саховский С.А., Колоскова Н.Н., Гончарова А.Ю., Миронков Б.Л., 20192019Саховский С.А., Колоскова Н.Н., Гончарова А.Ю., Миронков Б.Л.Sakhovsky S.A., Koloskova N.N., Goncharova A.Y., Mironkov B.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/1002

Одним из патогномоничных признаков болезни коронарных артерий пересаженного сердца является концентрическая гиперплазия интимы, которая может оцениваться внутрисосудистыми методами визуализации. Раннее выявление васкулопатии трансплантата и своевременная коррекция иммуносупрессивной терапии могут способствовать замедлению патологического процесса и как следствие увеличивать продолжительность жизни трансплантата сердца. В последнее время все большее применение находит метод внутрисосудистой оптической когерентной томографии, который позволяет повысить точность оценки слоев сосудистой стенки и рассматривается как альтернатива внутрисосудистому ультразвуковому исследованию. Данный обзор посвящен использованию современных методов внутрисосудистой визуализации в ранней диагностике васкулопатии сердечного трансплантата и выявлении предикторов данного заболевания.

One of the pathognomonic signs of сardiac allograft vasculopathy is concentric intimal hyperplasia, which can be assessed by intravascular imaging techniques. Early detection of cardiac graft vasculopathy and timely correction of immunosuppressive therapy can help slow the pathological process and, as a result, increase the functional survival of the heart graft. Recently, the method of intravascular optical coherence tomography, which improves the accuracy of the assessment of the layers of the vascular wall and is considered as an alternative to intravascular ultrasound, is becoming more and more common. This review focuses on the importance of modern methods of intravascular imaging in the early diagnosis of cardiac graft vasculopathy and the identification of predictors of this disease.

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The authors declare that there are no conflicts of interest present.